{"id":7506,"date":"2025-09-14T17:14:45","date_gmt":"2025-09-14T17:14:45","guid":{"rendered":"https:\/\/info-eforie.ro\/index.php\/2025\/09\/14\/trei-miliarde-de-dolari-pentru-reteta-tineretii-pariul-lui-jeff-bezos\/"},"modified":"2025-09-14T17:14:45","modified_gmt":"2025-09-14T17:14:45","slug":"trei-miliarde-de-dolari-pentru-reteta-tineretii-pariul-lui-jeff-bezos","status":"publish","type":"post","link":"https:\/\/info-eforie.ro\/index.php\/2025\/09\/14\/trei-miliarde-de-dolari-pentru-reteta-tineretii-pariul-lui-jeff-bezos\/","title":{"rendered":"Trei miliarde de dolari pentru re\u021beta tinere\u021bii. Pariul lui Jeff Bezos"},"content":{"rendered":"
\n

Un startup fondat acum trei ani promite s\u0103 rescrie limitele biologiei \u0219i s\u0103 atace cel mai vechi du\u0219man al omului \u2013 \u00eemb\u0103tr\u00e2nirea. Numele lui: Altos Labs. Finan\u021bat cu 3 miliarde de dolari, \u00eentre investitori fiind men\u021bionat \u0219i Jeff Bezos, compania a adunat \u00een jurul ei laurea\u021bi Nobel \u0219i pionieri ai medicinei regenerative. Obiectivul? S\u0103 redea celulelor corpului uman \u201etinere\u021bea pierdut\u0103\u201d \u0219i odat\u0103 cu ea rezisten\u021ba la boli \u0219i traumatisme.<\/p>\n

\"Miliardarul<\/picture>\n

Miliardarul Jeff Bezos\/FOTO:Arhiva<\/p>\n<\/div>\n

Primele rezultate nu mai apar doar \u00een comunicate spectaculoase, ci \u00een reviste \u0219tiin\u021bifice cu factor de impact. \u00cen ele se contureaz\u0103 un viitor \u00een care organismul ar putea fi \u201ereprogramat\u201d la nivel celular, astfel \u00eenc\u00e2t ADN-ul s\u0103 r\u0103m\u00e2n\u0103 t\u00e2n\u0103r. Inteligen\u021ba artificial\u0103 completeaz\u0103 tabloul, oferind, dup\u0103 cum spun autorii, \u201eo cale de sc\u0103pare din fa\u021ba \u00eemb\u0103tr\u00e2nirii\u201d.<\/p>\n

\u201eFactorii Yamanaka\u201d \u2013 cheia re\u00eentineririi<\/h2>\n

Numele lui Shinya Yamanaka, laureat al Premiului Nobel pentru Medicin\u0103, e deja legat de aceast\u0103 revolu\u021bie. \u00cen urm\u0103 cu dou\u0103 decenii, el a demonstrat c\u0103 celulele pielii pot fi readuse \u00eentr-o stare asem\u0103n\u0103toare celor embrionare, capabile s\u0103 se transforme \u00een orice \u021besut. Descoperirea a purtat numele de \u201efactori Yamanaka\u201d.<\/p>\n

Pe aceast\u0103 baz\u0103, biologul Juan Carlos Izpisua Belmonte, acum la Altos, a mers mai departe: a aplicat tehnica pe \u0219oareci \u0219i a ob\u021binut semne clare de \u00eentinerire. Un fel de \u201eelixir al vie\u021bii\u201d, dar cu riscuri uria\u0219e \u2013 prea mult\u0103 reprogramare ducea la apari\u021bia tumorilor.<\/p>\n

Aici intervine cercetarea condus\u0103 de profesorul Wolf Reik \u00een Marea Britanie. Echipa sa \u00eencearc\u0103 s\u0103 descifreze \u201eceasul transcrip\u021bional\u201d al celulelor \u2013 mecanismul care dicteaz\u0103 ce gene se activeaz\u0103 \u0219i c\u00e2nd. Dac\u0103 acest ceas poate fi controlat, terapia ar putea \u00eentineri celulele f\u0103r\u0103 pericolul cancerului, scrie The Times.<\/p>\n

B\u0103t\u0103lia cu \u201ederiva mezodermal\u0103\u201d<\/h2>\n

\u00cemb\u0103tr\u00e2nirea nu \u00eenseamn\u0103 doar riduri. O problem\u0103 major\u0103 este \u201ederiva mezodermal\u0103\u201d: celulele \u00ee\u0219i pierd treptat func\u021bia \u0219i \u00eencep s\u0103 se comporte ca ni\u0219te \u201ereparatori universali\u201d. Rezultatul? Inflama\u021bii cronice, fibroz\u0103, sc\u0103derea eficien\u021bei organelor.<\/p>\n

Belmonte estimeaz\u0103 c\u0103, dac\u0103 aceste procese ar putea fi oprite, via\u021ba uman\u0103 s-ar putea prelungi cu zeci de ani. \u00centr-un articol recent \u00een revista Cell, echipa sa arat\u0103 c\u0103 prin dezactivarea unor gene precise, celulele \u00ee\u0219i recap\u0103t\u0103 disciplina \u0219i \u201etinere\u021bea func\u021bional\u0103\u201d.<\/p>\n

H\u0103r\u021bile digitale ale tinere\u021bii<\/h2>\n

La Altos lucreaz\u0103 \u0219i Tore Graepel, cunoscut pentru contribu\u021bia la programul AlphaGo. Rolul lui: s\u0103 construiasc\u0103 modele computa\u021bionale ale \u00eemb\u0103tr\u00e2nirii.<\/p>\n

Imagina\u021bi-v\u0103 celulele corpului ca pe un peisaj de dealuri \u0219i v\u0103i. Tinere\u021bea \u00eenseamn\u0103 celule aflate sus, pe culmi, flexibile \u0219i pline de op\u021biuni. Cu timpul, ele alunec\u0103 \u00een v\u0103i, mai stabile, dar mai pu\u021bin adaptabile. \u00cemb\u0103tr\u00e2nirea este, de fapt, acest proces lent de \u201ealunecare \u00een vale\u201d.<\/p>\n

Graepel \u0219i echipa lui vor s\u0103 g\u0103seasc\u0103 h\u0103r\u021bile care arat\u0103 cum s\u0103 sco\u021bi celulele din aceste v\u0103i \u0219i s\u0103 le aduci \u00eenapoi pe culmi. Un fel de \u201erec\u0103lire celular\u0103\u201d, inspirat\u0103 din metalurgie. Dac\u0103 va reu\u0219i, medicii ar putea avea \u00eentr-o zi busola care s\u0103 le spun\u0103 unde se afl\u0103 fiecare celul\u0103 \u0219i cum s\u0103 o readuc\u0103 la tinere\u021be.<\/p>\n<\/p><\/div>\n

Read More<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"

Un startup fondat acum trei ani promite s\u0103 rescrie limitele biologiei \u0219i s\u0103 atace cel mai vechi du\u0219man al omului \u2013 \u00eemb\u0103tr\u00e2nirea. Numele lui: Altos […]<\/p>\n","protected":false},"author":1,"featured_media":7507,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_monsterinsights_skip_tracking":false,"_monsterinsights_sitenote_active":false,"_monsterinsights_sitenote_note":"","_monsterinsights_sitenote_category":0,"footnotes":""},"categories":[6],"tags":[],"class_list":["post-7506","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-popular"],"aioseo_notices":[],"_links":{"self":[{"href":"https:\/\/info-eforie.ro\/index.php\/wp-json\/wp\/v2\/posts\/7506","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/info-eforie.ro\/index.php\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/info-eforie.ro\/index.php\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/info-eforie.ro\/index.php\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/info-eforie.ro\/index.php\/wp-json\/wp\/v2\/comments?post=7506"}],"version-history":[{"count":0,"href":"https:\/\/info-eforie.ro\/index.php\/wp-json\/wp\/v2\/posts\/7506\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/info-eforie.ro\/index.php\/wp-json\/wp\/v2\/media\/7507"}],"wp:attachment":[{"href":"https:\/\/info-eforie.ro\/index.php\/wp-json\/wp\/v2\/media?parent=7506"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/info-eforie.ro\/index.php\/wp-json\/wp\/v2\/categories?post=7506"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/info-eforie.ro\/index.php\/wp-json\/wp\/v2\/tags?post=7506"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}